Xiaofei Carl Zang
Computational Biology & Transcriptomics. Postdoc at CHOP.
Hi! I’m Carl. I am a postdoc fellow in the Center for Computational and Genomic Medicine at the Children’s Hospital of Philadelphia, supervised by Dr. Yi Xing. I received my Ph.D. in Bioinformatics & Genomics from The Pennsylvania State University, advised by Dr. Mingfu Shao. Before my Ph.D. study, I obtained my B.S. in Cell & Molecular Biology with First Class Honors from The Chinese University of Hong Kong.
My research is on developing computational methods to advance transcriptome analysis and address challenges in RNA sequencing and assembly. My research integrates algorithms, machine learning, and biological insights to investigate problems such as alternative splicing, allele-specific expression, and transcript assembly using various sequencing technologies.
news
| Jul 07, 2025 | I joined Prof. Yi Xing’s group at the Children’s Hospital of Philadelphia as a postdoc scholar. Looking forward to the new exciting research and life in Philly! \(\) |
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| Jul 06, 2025 | My paper “Anchorage Accurately Assembles Anchor-flanked Synthetic Long Reads” is now published by Algorithms for Molecular Biology. |
| May 08, 2025 | I defended my PhD dissertation! 📚🎓🎉 |
| Mar 24, 2025 | My work on a novel computational method for single-cell RNA-seq assembly was accepted to GLBIO’25 for oral presentation. |
| Oct 02, 2024 | I presented my work “Augmenting Transcriptome Annotations through the Lens of Splicing Evolution” in Bioinformatics Method Developers Community Day at Penn State. Update Nov ‘24: This work “TENNIS” is available as a preprint. |
latest posts
| Nov 17, 2024 | Publish Python packages to PyPI (pip) |
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| Sep 26, 2024 | Strandness of RNA-seq and Transcripts Explained |
| Dec 02, 2021 | Anaconda getting started |