Xiaofei Carl Zang
Computational Biology & Transcriptomics. Postdoc at CHOP.
Hi! I’m Carl. I am a postdoc fellow in the Center for Computational and Genomic Medicine at the Children’s Hospital of Philadelphia, supervised by Dr. Yi Xing. I received my Ph.D. in Bioinformatics & Genomics from The Pennsylvania State University, advised by Dr. Mingfu Shao. Before my Ph.D. study, I obtained my B.S. in Cell & Molecular Biology with First Class Honors from The Chinese University of Hong Kong.
My research is on developing computational methods to advance transcriptome analysis and address challenges in RNA sequencing and assembly. My research integrates algorithms, machine learning, and biological insights to investigate problems such as alternative splicing, allele-specific expression, and transcript assembly using various sequencing technologies.
news
| May 24, 2026 | My paper “Augmenting Transcriptome Annotations through the Lens of Splicing Evolution” has been accepted by Genome Research ! |
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| Apr 02, 2026 | My paper “Amaranth: Enhanced Single-Cell Transcript Assembly via Discriminative Modeling of UMI Reads and Internal Reads” has been accepted to ISMB 2026! |
| Jul 07, 2025 | I joined Prof. Yi Xing’s group at the Children’s Hospital of Philadelphia as a postdoc scholar. Looking forward to the new exciting research and life in Philly! |
| Jul 06, 2025 | My paper “Anchorage Accurately Assembles Anchor-flanked Synthetic Long Reads” is now published by Algorithms for Molecular Biology. |
| May 08, 2025 | I defended my PhD dissertation! 📚🎓🎉 |
latest posts
| Feb 28, 2026 | Switching from conda to pixi |
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| Aug 24, 2025 | Nextflow StackOverflowError due to undefined workflow metadata |
| Nov 17, 2024 | Publish Python packages to PyPI (pip) |